Study title:
Dossier withdrawn by the notifier
Long title:
Phase 3, Open-Label, Single-Arm Study to Evaluate the Efficacy and Safety of PF-07055480 (Recombinant AAV2/6 Human Factor VIII Gene Therapy) in Adult Male Participants with Moderately Severe to Severe Hemophilia A (FVIII:C≤1%)
Date receipt dossier:
12 nov 2020
EU record number:
B/BE/20/BVW6
EudraCT number:
2019-004451-37
Company / Sponsor:
Pfizer
Phase:
III
Treated organism:
Humans
Indication category:
Genetic disorders
Disease:
Adult males with moderately severe to severe Hemophilia A
Therapeutic approach:
Gene therapy
Genetic modification:
Non-replicating recombinant vector derived from adeno-associated virus AAV6 serotype, containing a codon-optimised version of the human Factor VIII gene
Method of transfer of nucleic acid of interest:
Non-replicating, non-integrating recombinant adeno-associated virus serotype 6 (AAV6)
Administered biological material:
Recombinant virus
Type of procedure:
Contained use and Deliberate release
Notes:
Dossier withdrawn by the notifier on 7 December 2020 (before the advice of the Biosafety Council is finalised)