| 
            ADP-0055-001           | 
                  
            A phase I, ascending dose, to evaluate safety and efficacy of ADP A2M4CD8 in HLA-A2+ patients with MAGE-A4 psoitives tumors           | 
                  
                  
            Humans           | 
                  
            MAGE-A4 specific T cell receptor (TCR) with a CD8α co-receptor             | 
              
          
                  | 
            B/BE/18/BVW7           | 
                  
            Phase III trial investigating a AAV vector containing a variant of human factor IX gene administered to adult subjects with severe or moderately-severe hemophilia B           | 
                  
                  
            Humans           | 
                  
            Recombinant adeno associated viral vector containing the wild type modified to express the Padua derivative of human coagulation factor IX cDNA           | 
              
          
                  | 
            Only notified under the "contained use" procedure. Dossier submitted on 01/02/2005.           | 
                  
            A Controlled, Randomised, Parallel Group, Multicentre Study of the Efficacy and Safety of Herpes Simplex Virus-Thymidine Kinase Gene Therapy (CereproTM), with Subsequent Ganciclovir, for the Treatment of Patients with Operable High-Grade Glioma            | 
                  
                  
            Humans           | 
                  
            Thymidine Kinase (HSV-TK1)           |