| 
            B/BE/18/BVW5           | 
                  
            A Phase 1b/2a study to assess the safety and tolerability of GM Lactococcus lactis in subjects with Type 1 Diabetes Mellitus           | 
                  
                  
            Humans           | 
                  
            Biologically contained strain of Lactococcus lactis, genetically modified to secrete human interleukin-10 and proinsulin           | 
              
          
                  | 
            B/BE/11/V3           | 
                  
            Evaluation of the safety and efficacy of the vaccine PB-116 in the control of porcine pleuropneumonia caused by Actinobacillus pleuropneumoniae           | 
                  
                  
            pigs           | 
                  
            no new genes but deletion of a segment of gene A from which depends the haemolytic activity of the pathogen           | 
              
          
                  | 
            B/BE/03/B3           | 
                  
            Phase I multicentre study of TG1024 (Adenovirus interleukin 2) in patients with metastatic melanoma or other advanced solid tumor cancers           | 
                  
                  
            Humans           | 
                  
            gene coding for human interleukin 2           | 
              
          
                  | 
            B/BE/02/B7           | 
                  
            Phase II study evaluating the clinical efficacy of TG4010 (MVA-MUC1-IL2) in patients with metastatic Renal Cell Carcinoma (RCC)            | 
                  
                  
            Humans           | 
                  
            sequences coding for the human MUC-1 antigen and IL-2           | 
              
          
                  | 
            B/BE/01/B7           | 
                  
            Specific immunotherapy against MUC-1 antigen - Study TG4010.04 : "Phase II study with TG4010(MVA-MUC-1-IL-2) in patients with metastatic breast cancer", Study TG4010.05 : "Phase II study with TG 4010 in patients with non small cell lung cancer"             | 
                  
                  
            Humans           | 
                  
            sequences coding for the human MUC-1 antigen and IL-2           |