| 
            COVID-19-101           | 
                  
            A randomized, placebo-controlled trial, to evaluate the safety and immunogenicity of the COVID-19 vaccine, a measles vector-based vaccine candidate against COVID-19 in healthy volunteers consisting of an unblinded dose escalation and a blinded treatment p           | 
                  
                  
            Humans           | 
                  
            Recombinant measles virus vaccine strain (Schwarz strain) expressing the Spike glycoprotein 1 from SARS-CoV2           | 
              
          
                  | 
            MB-CART2019.1           | 
                  
            A phase I/II safety, dose finding and feasibility trial of MB-CART2019.1 in patients with relapsed or resistant B-NHL           | 
                  
                  
            Humans           | 
                  
            CD19 and CD20 chimeric antigen receptor           | 
              
          
                  | 
            Only notified under the "contained use" procedure. Dossier submitted on 21/02/2018.           | 
                  
            Efficacy and safety of bilateral intravitreal injection of GS010: a randomized, double-masked, placebo-controlled trial in subjects affected with G11778A ND4 leber hereditary optic neuropathy for up to one year.           | 
                  
                  
            Humans           | 
                  
            human wild-type MT-NDA (mitochondrial NADH Dehydrogenase 4)           |