| MB-CART2019.1 | A phase I/II safety, dose finding and feasibility trial of MB-CART2019.1 in patients with relapsed or resistant B-NHL | Humans | CD19 and CD20 chimeric antigen receptor | 
          
                  | Only notified under the "contained use" procedure. Dossier submitted on 20/08/2018. | A Phase I/II study of the safety and efficacy of a single dose of autologous CRISPR-Cas9 modified CD34+ human hematopoietic stem and progenitor cells in subjects with severe sickle disease | Humans | Modified cells expressing Hemoglobin F (HbF) | 
          
                  | Only notified under the "contained use" procedure. Dossier submitted on 01/02/2005. | A Controlled, Randomised, Parallel Group, Multicentre Study of the Efficacy and Safety of Herpes Simplex Virus-Thymidine Kinase Gene Therapy (CereproTM), with Subsequent Ganciclovir, for the Treatment of Patients with Operable High-Grade Glioma | Humans | Thymidine Kinase (HSV-TK1) |